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Advances with Long Non-Coding RNAs in Diabetic Peripheral Neuropathy.

ABSTRACT: Long non-coding RNAs (?lncRNAs) ?are a group of non-coding RNAs longer than 200 nucleotides, which are defined as transcripts. The lncRNAs are involved in regulating gene expression at epigenetic, transcriptional, and post-transcriptional levels. Recent studies have found that lncRNA is closely related to many diseases like neurological diseases, endocrine and metabolic disorders. Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes mellitus. In this review, we highlight the latest research related to lncRNAs in DPN.

SUBMITTER: Wu M 

PROVIDER: S-EPMC7201007 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Advances with Long Non-Coding RNAs in Diabetic Peripheral Neuropathy.

Wu Men M   Feng Yonghao Y   Shi Xiaohong X  

Diabetes, metabolic syndrome and obesity : targets and therapy 20200430

Long non-coding RNAs (lncRNAs) are a group of non-coding RNAs longer than 200 nucleotides, which are defined as transcripts. The lncRNAs are involved in regulating gene expression at epigenetic, transcriptional, and post-transcriptional levels. Recent studies have found that lncRNA is closely related to many diseases like neurological diseases, endocrine and metabolic disorders. Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes mellitus. In this r  ...[more]

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