The Serum MicroRNA Signatures for Pancreatic Cancer Detection and Operability Evaluation.
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ABSTRACT:
SUBMITTER: Yan Q
PROVIDER: S-EPMC7201024 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
The Serum MicroRNA Signatures for Pancreatic Cancer Detection and Operability Evaluation.
Yan Qiuliang Q Hu Dandan D Li Maolan M Chen Yan Y Wu Xiangsong X Ye Qinghuang Q Wang Zhijiang Z He Lingzhe L Zhu Jinhui J
Frontiers in bioengineering and biotechnology 20200429
Pancreatic cancer (PC) has high morbidity and mortality. It is the fourth leading cause of cancer death. Its diagnosis and treatment are difficult. Liquid biopsy makes early diagnosis of pancreatic cancer possible. We analyzed the expression profiles of 2,555 serum miRNAs in 100 pancreatic cancer patients and 150 healthy controls. With advanced feature selection methods, we identified 13 pancreatic cancer signature miRNAs that can classify the pancreatic cancer patients and healthy controls. For ...[more]
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