Ontology highlight
ABSTRACT:
SUBMITTER: Kurita H
PROVIDER: S-EPMC7202611 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Kurita Hirofumi H Haruta Natsuki N Uchihashi Yoshito Y Seto Takahito T Takashima Kazunori K
PloS one 20200506 5
DNA damage in the A549 human lung cancer cell line treated with cold plasma irradiation was investigated. We confirmed that cold atmospheric plasma generated reactive oxygen and nitrogen species (RONS) in a liquid, and the intracellular RONS level was increased in plasma-irradiated cells. However, a notable decrease in cell viability was not observed 24 hours after plasma irradiation. Because RONS induce oxidative damage in cells, strand breaks and chemical modification of DNA in the cancer cell ...[more]