Facilitating Versus Inhibiting the Transmission of Drug Abuse from High-Risk Parents to Their Children: A Swedish National Study.

ABSTRACT: We seek to identify factors that facilitate or inhibit transmission of drug abuse (DA) from high-risk parents to their children. In 44,250 offspring of these parents, ascertained from a Swedish national sample for having a mother and/or father with DA, we explored, using Cox models, how the prevalence of DA was predicted by potentially malleable risk factors in these high-risk parents, their spouses and the rearing environment they provided. Analyses of offspring of discordant high-risk siblings and offspring of discordant sibling-in-laws and step-parents aided causal inference. Risk for DA in the children was associated with high-risk and married-in parental externalizing psychopathology, a range of other features of these parents (e.g., low education and receipt of welfare), and aspects

SUBMITTER: Kendler KS 

PROVIDER: S-EPMC7202959 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature