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Potential SARS-CoV-2 Preimmune IgM Epitopes.

ABSTRACT: While studying the human public IgM igome as represented by a library of 224,087 linear mimotopes, three exact matches to peptides in the proteins of SARS-CoV-2 were found: two in the open reading frame 1ab and one in the spike protein. Joining the efforts to fast track SARS-CoV-2 vaccine development, here we describe briefly these potential epitopes in comparison to mimotopes representing peptides of SARS-CoV, HCoV 229E and OC43.

SUBMITTER: Shivarov V

PROVIDER: S-EPMC7203467 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Potential SARS-CoV-2 Preimmune IgM Epitopes.

Shivarov Velizar V Petrov Peter K PK Pashov Anastas D AD

Frontiers in immunology 20200430

While studying the human public IgM igome as represented by a library of 224,087 linear mimotopes, three exact matches to peptides in the proteins of SARS-CoV-2 were found: two in the open reading frame 1ab and one in the spike protein. Joining the efforts to fast track SARS-CoV-2 vaccine development, here we describe briefly these potential epitopes in comparison to mimotopes representing peptides of SARS-CoV, HCoV 229E and OC43. ...[more]

PMID: 32425955

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