Phagocytic Integrins: Activation and Signaling.
Ontology highlight
ABSTRACT:
SUBMITTER: Torres-Gomez A
PROVIDER: S-EPMC7203660 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Phagocytic Integrins: Activation and Signaling.
Torres-Gomez Alvaro A Cabañas Carlos C Lafuente Esther M EM
Frontiers in immunology 20200430
Phagocytic integrins are endowed with the ability to engulf and dispose of particles of different natures. Evolutionarily conserved from worms to humans, they are involved in pathogen elimination and apoptotic and tumoral cell clearance. Research in the field of integrin-mediated phagocytosis has shed light on the molecular events controlling integrin activation and their effector functions. However, there are still some aspects of the regulation of the phagocytic process that need to be clarifi ...[more]
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