Dataset Information

New Diagnosis Test under the Neutrosophic Statistics: An Application to Diabetic Patients.

ABSTRACT: The diagnosis tests (DT) under classical statistics are applied under the assumption that all observations in the data are determined. Therefore, these DT cannot be applied for the analysis of the data when some or all observations are not determined. The neutrosophic statistics (NS) which is the extension of classical statistics can be applied for the data having uncertain, unclear, and fuzzy observations. In this paper, we will present the DT, and gold-standard tests under NS are called neutrosophic diagnosis tests (NDT). Therefore, the proposed NDT is the generalization of the existing DT and can be applied under the uncertainty environment. We will present the NDT table and present a real example from the medical field. The use of the proposed method will be more effective and adequate to be used in medical science, biostatistics, decision, and classification analysis.

SUBMITTER: Aslam M

PROVIDER: S-EPMC7204183 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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New Diagnosis Test under the Neutrosophic Statistics: An Application to Diabetic Patients.

Aslam Muhammad M Arif Osama H OH Sherwani Rehan Ahmad Khan RAK

BioMed research international 20200122

The diagnosis tests (DT) under classical statistics are applied under the assumption that all observations in the data are determined. Therefore, these DT cannot be applied for the analysis of the data when some or all observations are not determined. The neutrosophic statistics (NS) which is the extension of classical statistics can be applied for the data having uncertain, unclear, and fuzzy observations. In this paper, we will present the DT, and gold-standard tests under NS are called neutro ...[more]

PMID: 32420326

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Project description:BackgroundEarly diagnosis for the diabetes complications is clinically demanding with great significancy. Regarding the complexity of diabetes complications, we applied a multi-label classification (MLC) model to predict four diabetic complications simultaneously using data in the modern electronic health records (EHRs), and leveraged the correlations between the complications to further improve the prediction accuracy.MethodsWe obtained the demographic characteristics and laboratory data from the EHRs for patients admitted to Changzhou No. 2 People's Hospital, the affiliated hospital of Nanjing Medical University in China from May 2013 to June 2020. The data included 93 biochemical indicators and 9,765 patients. We used the Pearson correlation coefficient (PCC) to analyze the correlations between different diabetic complications from a statistical perspective. We used an MLC model, based on the Random Forest (RF) technique, to leverage these correlations and predict four complications simultaneously. We explored four different MLC models; a Label Power Set (LP), Classifier Chains (CC), Ensemble Classifier Chains (ECC), and Calibrated Label Ranking (CLR). We used traditional Binary Relevance (BR) as a comparison. We used 11 different performance metrics and the area under the receiver operating characteristic curve (AUROC) to evaluate these models. We analyzed the weights of the learned model and illustrated (1) the top 10 key indicators of different complications and (2) the correlations between different diabetic complications.ResultsThe MLC models including CC, ECC and CLR outperformed the traditional BR method in most performance metrics; the ECC models performed the best in Hamming loss (0.1760), Accuracy (0.7020), F1_Score (0.7855), Precision (0.8649), F1_micro (0.8078), F1_macro (0.7773), Recall_micro (0.8631), Recall_macro (0.8009), and AUROC (0.8231). The two diabetic complication correlation matrices drawn from the PCC analysis and the MLC models were consistent with each other and indicated that the complications correlated to different extents. The top 10 key indicators given by the model are valuable in medical application.ConclusionsOur MLC model can effectively utilize the potential correlation between different diabetic complications to further improve the prediction accuracy. This model should be explored further in other complex diseases with multiple complications.

Dataset Information

New Diagnosis Test under the Neutrosophic Statistics: An Application to Diabetic Patients.

Publications

New Diagnosis Test under the Neutrosophic Statistics: An Application to Diabetic Patients.

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