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Factors Influencing the Onset of Neoadjuvant Therapy in Breast Cancer Patients.


ABSTRACT:

Background

Time to treatment onset (TTTO) is critical in breast cancer patients receiving neoadjuvant chemotherapy (NACT). We therefore investigated possible delaying factors of therapy onset.

Methods

All patients were included who qualified for NACT in our hospital from 2015 to 2017. The time interval between core biopsy of tumor and date of therapy onset was defined as primary endpoint. Among other things, age, out- and in-patient presentation, and study or standard treatment were investigated as potentially delaying factors.

Results

We analyzed 139 patients scheduled for NACT; 90 (64.7%) received standard NACT, and 49 (35.3%) were recruited for trials. The average age was 53 years (±13.2 years). A time interval of 30.7 days (±11.8 days) was seen between diagnosis a

SUBMITTER: Muller C 

PROVIDER: S-EPMC7204773 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature