Ontology highlight
ABSTRACT:
SUBMITTER: Jia Y
PROVIDER: S-EPMC7205816 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Jia Yan Y Jin Huanhuan H Gao Liyuan L Yang Xiang X Wang Feixia F Ding Hai H Chen Anping A Tan Shanzhong S Zhang Feng F Shao Jiangjuan J Wang Shijun S Zheng Shizhong S
Journal of cellular and molecular medicine 20200403 9
A growing number of studies recognize that long non-coding RNAs (lncRNAs) are essential to mediate multiple tumorigenic processes, including hepatic tumorigenesis. However, the pathological mechanism of lncRNA-regulated liver cancer cell growth remains poorly understood. In this study, we identified a novel function lncRNA, named polo-like kinase 4 associated lncRNA (lncRNA PLK4, GenBank Accession No. RP11-50D9.3), whose expression was dramatically down-regulated in hepatocellular carcinoma (HCC ...[more]