MicroRNA regulatory networks in the pathogenesis of sarcopenia.
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ABSTRACT:
SUBMITTER: Yin J
PROVIDER: S-EPMC7205827 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
MicroRNA regulatory networks in the pathogenesis of sarcopenia.
Yin Jiayu J Qian Zhiyuan Z Chen Yuqi Y Li Yi Y Zhou Xiang X
Journal of cellular and molecular medicine 20200412 9
Sarcopenia is an age-related disease characterized by disturbed homeostasis of skeletal muscle, leading to a decline in muscle mass and function. Loss of muscle mass and strength leads to falls and fracture, and is often accompanied by other geriatric diseases, including osteoporosis, frailty and cachexia, resulting in a general decrease in quality of life and an increase in mortality. Although the underlying mechanisms of sarcopenia are still not completely understood, there has been a marked i ...[more]
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