Ontology highlight
ABSTRACT:
SUBMITTER: Tixeira R
PROVIDER: S-EPMC7206021 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Tixeira Rochelle R Phan Thanh Kha TK Caruso Sarah S Shi Bo B Atkin-Smith Georgia K GK Nedeva Christina C Chow Jenny D Y JDY Puthalakath Hamsa H Hulett Mark D MD Herold Marco J MJ Poon Ivan K H IKH
Cell death and differentiation 20190501 1
Many cell types are known to undergo a series of morphological changes during the progression of apoptosis, leading to their disassembly into smaller membrane-bound vesicles known as apoptotic bodies (ApoBDs). In particular, the formation of circular bulges called membrane blebs on the surface of apoptotic cells is a key morphological step required for a number of cell types to generate ApoBDs. Although apoptotic membrane blebbing is thought to be regulated by kinases including ROCK1, PAK2 and L ...[more]