Ontology highlight
ABSTRACT:
SUBMITTER: Senichkin VV
PROVIDER: S-EPMC7206148 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Senichkin Viacheslav V VV Streletskaia Alena Y AY Gorbunova Anna S AS Zhivotovsky Boris B Kopeina Gelina S GS
Cell death and differentiation 20200106 2
The members of the Bcl-2 family are the central regulators of various cell death modalities. Some of these proteins contribute to apoptosis, while others counteract this type of programmed cell death, thus balancing cell demise and survival. A disruption of this balance leads to the development of various diseases, including cancer. Therefore, understanding the mechanisms that underlie the regulation of proteins of the Bcl-2 family is of great importance for biomedical research. Among the member ...[more]