Association of Individual-Level Factors With Visual Outcomes in Optic Neuritis: Secondary Analysis of a Randomized Clinical Trial.

ABSTRACT: Importance:Using corticosteroids to treat acute demyelinating optic neuritis has been identified as an area for shared decision-making. However, no analysis exists to support personalized shared decision-making that considers long- and short-term treatment benefits. Objective:To develop models of individual-level visual outcomes for patients with optic neuritis. Design, Setting, and Participants:This secondary analysis of the Optic Neuritis Treatment Trial (ONTT), a randomized clinical trial, was performed at 14 academic eye centers and 1 large community eye center. Adults aged 18 to 46 years with incident acute unilateral optic neuritis within 8 days of vision loss onset were included. Data were collected from July 1988 to June 1991, downloaded on October 15, 2018, and analyzed from Janua

SUBMITTER: De Lott LB 

PROVIDER: S-EPMC7206503 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature