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WFhb1-1 plays an important role in resistance against Fusarium head blight in wheat.


ABSTRACT: Fusarium head blight (FHB) is a severe disease of wheat (Triticum aestivum L.). Qfhb1 is the most important quantitative trait locus (QTL) for FHB resistance. We previously identified wheat gene WFhb1-1 (aka WFhb1-c1) as a candidate for FHB resistance gene. Here we report that WFhb1-1 has been cloned. The gene (GenBank # KU304333.1) consists of a single exon, encoding a putative membrane protein of 127 amino acids. WFhb1-1 protein produced in Pichia pastoris inhibits growth of both F. graminearum and P. pastoris in culture. Western Blotting with anti- WFhb1-1 antibody revealed a significant decrease (p?

SUBMITTER: Paudel B 

PROVIDER: S-EPMC7210279 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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WFhb1-1 plays an important role in resistance against Fusarium head blight in wheat.

Paudel Bimal B   Zhuang Yongbin Y   Galla Aravind A   Dahal Subha S   Qiu Yinjie Y   Ma Anjun A   Raihan Tajbir T   Yen Yang Y  

Scientific reports 20200508 1


Fusarium head blight (FHB) is a severe disease of wheat (Triticum aestivum L.). Qfhb1 is the most important quantitative trait locus (QTL) for FHB resistance. We previously identified wheat gene WFhb1-1 (aka WFhb1-c1) as a candidate for FHB resistance gene. Here we report that WFhb1-1 has been cloned. The gene (GenBank # KU304333.1) consists of a single exon, encoding a putative membrane protein of 127 amino acids. WFhb1-1 protein produced in Pichia pastoris inhibits growth of both F. graminearu  ...[more]

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