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A case of multi-agent drug resistant choriocarcinoma treated with Pembrolizumab.


ABSTRACT: •High-risk multi-agent drug resistant GTN is a life threatening disease.•Majority of choriocarcinomas show intense PD-L1 immunoreactivity.•Pembrolizumab increases antitumor activity.•Effectiveness of Pembrolizumab in treating patients with high-risk multi-agent drug resistant GTN.

SUBMITTER: Goldfarb JA 

PROVIDER: S-EPMC7210394 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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A case of multi-agent drug resistant choriocarcinoma treated with Pembrolizumab.

Goldfarb Jennifer A JA   Dinoi Giorgia G   Mariani Andrea A   Langstraat Carrie L CL  

Gynecologic oncology reports 20200423


•High-risk multi-agent drug resistant GTN is a life threatening disease.•Majority of choriocarcinomas show intense PD-L1 immunoreactivity.•Pembrolizumab increases antitumor activity.•Effectiveness of Pembrolizumab in treating patients with high-risk multi-agent drug resistant GTN. ...[more]

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