Predicting worse survival for newly diagnosed T cell lymphoma based on the decreased baseline CD16-/CD16?+?monocyte ratio.
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ABSTRACT:
SUBMITTER: Zhang W
PROVIDER: S-EPMC7211003 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
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Predicting worse survival for newly diagnosed T cell lymphoma based on the decreased baseline CD16-/CD16 + monocyte ratio.
Zhang Wei W Ruan Jing J Zhou Daobin D Han Xiao X Zhang Yan Y Wang Wei W Ouyang Mingqi M
Scientific reports 20200508 1
T cell non-Hodgkin lymphoma (T-NHL) is highly invasive and heterogeneous without accurate prognosis prediction. We proposed peripheral CD16-/CD16 + monocytes the additional indicators for T-NHL prognosis. We prospectively recruited 31 T-NHL patients without previous treatment. The CD16-/CD16 + monocyte ratio before chemotherapy was calculated and regular follow up was performed to calculate prognostic prediction value. Tumor associated macrophages (TAM) in tumor tissue were counted and transcrip ...[more]
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