Ontology highlight
ABSTRACT:
SUBMITTER: Zhang F
PROVIDER: S-EPMC7214166 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Zhang Fuping F Wang Chengshi C Wen Xin X Chen Yang Y Mao Ruiwen R Cui Danli D Li Lan L Liu Jingping J Chen Younan Y Cheng Jingqiu J Lu Yanrong Y
Journal of cellular and molecular medicine 20200413 10
Diabetic nephropathy (DN) as a kind of serious microvascular complication of Diabetes Mellitus (DM) usually causes the end-stage of renal disease (ESRD). Studies have demonstrated that CD103<sup>+</sup> dendritic cells (DCs) exhibited a renal pathogenic effect in murine chronic kidney disease (CKD). Mesenchymal stem cells (MSCs) can alleviate DN and suppress the DCs maturation. To explore the role of CD103<sup>+</sup> DCs and the potential mechanisms underlying MSCs-mediated protective effects i ...[more]