Key genes of renal tubular necrosis: a bioinformatics analysis.
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ABSTRACT:
SUBMITTER: Lin P
PROVIDER: S-EPMC7215026 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Publications
Key genes of renal tubular necrosis: a bioinformatics analysis.
Lin Peng P Pan Yongqing Y Chen Hang H Jiang Ling L Liao Yunhua Y
Translational andrology and urology 20200401 2
<h4>Background</h4>To explore the key genes in renal tubular necrosis.<h4>Methods</h4>Microarray datasets GSE69644, GSE27168, and GSE2027 were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) were identified and we performed functional enrichment analysis. The network of protein interaction and gene interaction was constructed, and the module analysis was conducted using Cytoscape.<h4>Results</h4>A total of 543 DEGs and 13 hub genes were identified. The ...[more]
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