Ontology highlight
ABSTRACT:
SUBMITTER: Leu SJ
PROVIDER: S-EPMC7215377 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Leu Sy-Jye SJ Lee Yu-Ching YC Lee Chi-Hsin CH Liao Po-Yen PY Chiang Chen-Wei CW Yang Chieh-Ming CM Su Ching-Hua CH Ou Tsong-Yih TY Liu Ko-Jiunn KJ Lo Hsiu-Jung HJ Tsai Bor-Yu BY Yang Yi-Yuan YY
International journal of molecular sciences 20200421 8
<i>Candida albicans</i> (<i>C. albicans</i>) is an opportunistic human pathogen responsible for approximately a half of clinical candidemia. The emerging <i>Candida</i> spp. with resistance to azoles is a major challenge in clinic, suggesting an urgent demand for new drugs and therapeutic strategies. Alpha-enolase (Eno1) is a multifunctional protein and represents an important marker for invasive candidiasis. Thus, <i>C. albicans</i> Eno1 (CaEno1) is believed to be an important target for the de ...[more]