Nuclear Functions of the Tyrosine Kinase Src.
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ABSTRACT:
SUBMITTER: Bagnato G
PROVIDER: S-EPMC7215861 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Publications
Nuclear Functions of the Tyrosine Kinase Src.
Bagnato Giulia G Leopizzi Martina M Urciuoli Enrica E Peruzzi Barbara B
International journal of molecular sciences 20200411 8
Src is the representative member of the Src-family kinases (SFKs), a group of tyrosine kinases involved in several cellular processes. Its main function has been for long confined to the plasma membrane/cytoplasm compartment, being a myristoylated protein anchored to the cell membrane and functioning downstream to receptors, most of them lacking intrinsic kinase activity. In the last decades, new roles for some SFKs have been described in the nuclear compartment, suggesting that these proteins c ...[more]
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