Unknown

Dataset Information

0

Maternal Glucose Concentrations in Early Pregnancy and Cardiometabolic Risk Factors in Childhood.


ABSTRACT: OBJECTIVE:This study aimed to examine the associations of maternal early-pregnancy glucose and insulin concentrations with offspring cardiometabolic risk factors and fat distribution. METHODS:In a population-based prospective cohort study among 3,737 mothers and their children, random maternal glucose and insulin concentrations were measured at a median gestational age of 13.2 (95% range 10.5-17.1) weeks. Childhood fat, blood pressure, and blood concentrations of lipids, glucose, and insulin at the age of 10 years were measured. RESULTS:Higher maternal early-pregnancy glucose and insulin concentrations were associated with a higher risk of childhood overweight, and higher maternal early-pregnancy insulin concentrations were associated with an increased childhood risk of clustering of cardiometabolic risk factors (all P?

SUBMITTER: Wahab RJ 

PROVIDER: S-EPMC7216879 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

altmetric image

Publications

Maternal Glucose Concentrations in Early Pregnancy and Cardiometabolic Risk Factors in Childhood.

Wahab Rama J RJ   Voerman Ellis E   Jansen Pauline W PW   Oei Edwin H G EHG   Steegers Eric A P EAP   Jaddoe Vincent W V VWV   Gaillard Romy R  

Obesity (Silver Spring, Md.) 20200501 5


<h4>Objective</h4>This study aimed to examine the associations of maternal early-pregnancy glucose and insulin concentrations with offspring cardiometabolic risk factors and fat distribution.<h4>Methods</h4>In a population-based prospective cohort study among 3,737 mothers and their children, random maternal glucose and insulin concentrations were measured at a median gestational age of 13.2 (95% range 10.5-17.1) weeks. Childhood fat, blood pressure, and blood concentrations of lipids, glucose,  ...[more]

Similar Datasets

| S-EPMC8699579 | biostudies-literature
| S-EPMC6353674 | biostudies-literature
| S-EPMC5861539 | biostudies-literature
| S-EPMC6669102 | biostudies-literature
| S-EPMC10005748 | biostudies-literature
| S-EPMC7487846 | biostudies-literature
| S-EPMC5894958 | biostudies-literature
| S-EPMC10868575 | biostudies-literature
| S-EPMC8295375 | biostudies-literature
| S-EPMC7877074 | biostudies-literature