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Thalamic, cortical, and amygdala involvement in the processing of a natural sound cue of danger.

ABSTRACT: Animals use auditory cues generated by defensive responses of others to detect impending danger. Here we identify a neural circuit in rats involved in the detection of one such auditory cue, the cessation of movement-evoked sound resulting from freezing. This circuit comprises the dorsal subnucleus of the medial geniculate body (MGD) and downstream areas, the ventral area of the auditory cortex (VA), and the lateral amygdala (LA). This study suggests a role for the auditory offset pathway in processing a natural sound cue of threat.

SUBMITTER: Pereira AG

PROVIDER: S-EPMC7217448 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Thalamic, cortical, and amygdala involvement in the processing of a natural sound cue of danger.

Pereira Ana G AG Farias Matheus M Moita Marta A MA

PLoS biology 20200512 5

Animals use auditory cues generated by defensive responses of others to detect impending danger. Here we identify a neural circuit in rats involved in the detection of one such auditory cue, the cessation of movement-evoked sound resulting from freezing. This circuit comprises the dorsal subnucleus of the medial geniculate body (MGD) and downstream areas, the ventral area of the auditory cortex (VA), and the lateral amygdala (LA). This study suggests a role for the auditory offset pathway in pro ...[more]

PMID: 32396574

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