Ontology highlight
ABSTRACT:
SUBMITTER: Abramson A
PROVIDER: S-EPMC7218658 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Abramson Alex A Caffarel-Salvador Ester E Soares Vance V Minahan Daniel D Tian Ryan Yu RY Lu Xiaoya X Dellal David D Gao Yuan Y Kim Soyoung S Wainer Jacob J Collins Joy J Tamang Siddartha S Hayward Alison A Yoshitake Tadayuki T Lee Hsiang-Chieh HC Fujimoto James J Fels Johannes J Frederiksen Morten Revsgaard MR Rahbek Ulrik U Roxhed Niclas N Langer Robert R Traverso Giovanni G
Nature medicine 20191007 10
Insulin and other injectable biologic drugs have transformed the treatment of patients suffering from diabetes<sup>1,2</sup>, yet patients and healthcare providers often prefer to use and prescribe less effective orally dosed medications<sup>3-5</sup>. Compared with subcutaneously administered drugs, oral formulations create less patient discomfort<sup>4</sup>, show greater chemical stability at high temperatures<sup>6</sup>, and do not generate biohazardous needle waste<sup>7</sup>. An oral dos ...[more]