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Cholesterol functionalized aliphatic N-substituted 8-membered cyclic carbonate.


ABSTRACT: Straightforward synthesis of cholesterol functionalized aliphatic N-substituted 8-membered cyclic carbonate (Chol-8m) monomer is reported. Well-defined poly(ethylene glycol) (PEG) diblock copolymers were readily accessed via organo catalytic ring opening polymerization. These polymers show promise as building blocks for self-assembled nanostructures and steric stabilizers for liposomes.

SUBMITTER: Venkataraman S 

PROVIDER: S-EPMC7219653 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature

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Cholesterol functionalized aliphatic <i>N</i>-substituted 8-membered cyclic carbonate.

Venkataraman Shrinivas S   Mineart Kenneth P KP   Prabhu Vivek M VM   Hedrick James L JL   Yang Yi Yan YY  

Polymer chemistry 20180410 18


Straightforward synthesis of cholesterol functionalized aliphatic <i>N</i>-substituted 8-membered cyclic carbonate (Chol-8m) monomer is reported. Well-defined poly(ethylene glycol) (PEG) diblock copolymers were readily accessed via organo catalytic ring opening polymerization. These polymers show promise as building blocks for self-assembled nanostructures and steric stabilizers for liposomes. ...[more]

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