Ontology highlight
ABSTRACT:
SUBMITTER: Lee J
PROVIDER: S-EPMC7219730 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Lee Junghee J Green Michael F MF Nuechterlein Keith H KH Swerdlow Neal R NR Greenwood Tiffany A TA Hellemann Gerhard S GS Lazzeroni Laura C LC Light Gregory A GA Radant Allen D AD Seidman Larry J LJ Siever Larry J LJ Silverman Jeremy M JM Sprock Joyce J Stone William S WS Sugar Catherine A CA Tsuang Debby W DW Tsuang Ming T MT Turetsky Bruce I BI Gur Ruben C RC Gur Raquel E RE Braff David L DL
PloS one 20200513 5
Recently emerging evidence indicates accelerated age-related changes in the structure and function of the brain in schizophrenia, raising a question about its potential consequences on cognitive function. Using a large sample of schizophrenia patients and controls and a battery of tasks across multiple cognitive domains, we examined whether patients show accelerated age-related decline in cognition and whether an age-related effect differ between females and males. We utilized data of 1,415 schi ...[more]