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Prognostic significance of red blood cell distribution width in gastrointestinal cancers: A meta-analysis.

ABSTRACT: BACKGROUND:Many publications showed red blood cell distribution width (RDW) might associate with the prognosis of gastrointestinal (GI) cancers, however, the agreement has not been reached because of controversial results. This meta-analysis aimed to explore the prognostic value of RDW in GI cancers. METHODS:Four common databases were comprehensively searched to look for relevant studies. The meta-analyses for overall survival (OS) and disease-free survival were performed using hazard ratio (HR) and 95% confidence interval (CI), and the meta-analyses for clinical parameters were conducted using odd ratio and 95% CI. RESULTS:A total of 13 studies involving with 3,509 patients with GI cancers were included into this study. The results showed, compared to patients with low RDW, patients with high RDW tended to have shorter OS (HR?=?1.75, 95%CI?=?1.57-1.94, P?

SUBMITTER: Zhou Y

PROVIDER: S-EPMC7220356 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Prognostic significance of red blood cell distribution width in gastrointestinal cancers: A meta-analysis.

Zhou Yongping Y Li Xiding X Lu Zhihua Z Zhang Lei L Dai Tu T

Medicine 20200401 16

<h4>Background</h4>Many publications showed red blood cell distribution width (RDW) might associate with the prognosis of gastrointestinal (GI) cancers, however, the agreement has not been reached because of controversial results. This meta-analysis aimed to explore the prognostic value of RDW in GI cancers.<h4>Methods</h4>Four common databases were comprehensively searched to look for relevant studies. The meta-analyses for overall survival (OS) and disease-free survival were performed using ha ...[more]

PMID: 32311927

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