Ontology highlight
ABSTRACT:
SUBMITTER: O'Toole SA
PROVIDER: S-EPMC7220879 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
O'Toole Sharon A SA Spillane Cathy C Huang Yanmei Y Fitzgerald Marie C MC Ffrench Brendan B Mohamed Bashir B Ward Mark M Gallagher Michael M Kelly Tanya T O'Brien Cathal C Ruttle Carmel C Bogdanska Anna A Martin Cara C Mullen Dorinda D Connolly Elizabeth E McGarrigle Sarah A SA Kennedy John J O'Leary John J JJ
Breast cancer research and treatment 20200506 3
<h4>Purpose</h4>The association between pathological complete response (pCR) in patients receiving neoadjuvant chemotherapy (NAC) for breast cancer and Circulating Tumour Cells (CTCs) is not clear. The aim of this study was to assess whether CTC enumeration could be used to predict pathological response to NAC in breast cancer as measured by the Miller-Payne grading system.<h4>Methods</h4>Twenty-six patients were recruited, and blood samples were taken pre- and post-NAC. CTCs were isolated using ...[more]