Ontology highlight
ABSTRACT:
SUBMITTER: Christian D
PROVIDER: S-EPMC7221697 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20200417 8
Stress factors caused by inadequate storage can induce the unwanted degradation of active compounds in pharmaceutical formulations. Resonance Raman spectroscopy is presented as an analytical tool for rapid monitoring of small concentration changes of tetracycline and the metabolite 4-epianhydrotetracycline. These degradation processes were experimentally induced by changes in temperature, humidity, and irradiation with visible light over a time period of up to 23 days. The excitation wavelength ...[more]