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Association between anemia and hematological indices with mortality among cardiac intensive care unit patients.

ABSTRACT: BACKGROUND:Anemia and elevated red cell distribution width (RDW) or mean corpuscular volume (MCV) are associated with an adverse prognosis in patients with cardiovascular disease and critical illness. Limited data exist regarding these associations in unselected cardiac intensive care unit (CICU) patients. METHODS:Retrospective cohort study of CICU patients between January 1, 2007, and December 31, 2015, with a hemoglobin (Hb) level measured at admission. Multivariable regression was performed to determine predictors of hospital mortality, and Kaplan-Meier analysis was used to determine post-discharge survival. RESULTS:We included 9644 patients with a mean age of 67.5?±?15.1 years, including 3604 (37.4%) females. The median (IQR) values of Hb, MCV and RDW were 12.2 g/dL (10.6, 13.7), 90.7 fL (87.3, 94.2) fL, and 14.1% (13.3, 15.8), respectively. Anemia (admission Hb??0.1), while admission RDW (adjusted OR 1.12 per 1%, 95% CI 1.07-1.18, p?

SUBMITTER: Rayes HA 

PROVIDER: S-EPMC7224152 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Association between anemia and hematological indices with mortality among cardiac intensive care unit patients.

Rayes Hamza A HA   Vallabhajosyula Saraschandra S   Barsness Gregory W GW   Anavekar Nandan S NS   Go Ronald S RS   Patnaik Mrinal S MS   Kashani Kianoush B KB   Jentzer Jacob C JC  

Clinical research in cardiology : official journal of the German Cardiac Society 20190918 5

<h4>Background</h4>Anemia and elevated red cell distribution width (RDW) or mean corpuscular volume (MCV) are associated with an adverse prognosis in patients with cardiovascular disease and critical illness. Limited data exist regarding these associations in unselected cardiac intensive care unit (CICU) patients.<h4>Methods</h4>Retrospective cohort study of CICU patients between January 1, 2007, and December 31, 2015, with a hemoglobin (Hb) level measured at admission. Multivariable regression  ...[more]

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