In situ 3D-patterning of electrospun fibers using two-layer composite materials.

ABSTRACT: Polymeric electrospun nanofibers have extensive applications in filtration, sensing, drug delivery, and tissue engineering that often require the fibers to be patterned or integrated with a larger device. Here, we describe a highly versatile in situ strategy for three-dimensional electrospun fiber patterning using collectors with an insulative surface layer and conductive recessed patterns. We show that two-layer collectors with pattern dimensions down to 100-micrometers are easily fabricated using available laboratory equipment. We use finite element method simulation and experimental validation to demonstrate that the fiber patterning strategy is effective for a variety of pattern dimensions and fiber materials. Finally, the potential for this strategy to enable new applications of elect

SUBMITTER: Creighton RL 

PROVIDER: S-EPMC7224382 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature