Ontology highlight
ABSTRACT:
SUBMITTER: Baron VO
PROVIDER: S-EPMC7224385 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Baron Vincent O VO Chen Mingzhou M Hammarstrom Björn B Hammond Robert J H RJH Glynne-Jones Peter P Gillespie Stephen H SH Dholakia Kishan K
Communications biology 20200514 1
Tuberculosis (TB) remains a leading cause of death worldwide. Lipid rich, phenotypically antibiotic tolerant, bacteria are more resistant to antibiotics and may be responsible for relapse and the need for long-term TB treatment. We present a microfluidic system that acoustically traps live mycobacteria, M. smegmatis, a model organism for M. tuberculosis. We then perform optical analysis in the form of wavelength modulated Raman spectroscopy (WMRS) on the trapped M. smegmatis for up to eight hour ...[more]