Ontology highlight
ABSTRACT:
SUBMITTER: Facciorusso A
PROVIDER: S-EPMC7225931 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Facciorusso Antonio A Abd El Aziz Mohamed A MA Singh Siddharth S Pusceddu Sara S Milione Massimo M Giacomelli Luca L Sacco Rodolfo R
Cancers 20200403 4
Statins can decrease hepatocellular carcinoma (HCC) occurrence, but the magnitude and the predictors of these effects remain unclear. This meta-analysis provides a pooled estimate of the impact of statin use on HCC occurrence. Pooled effects were calculated using a random-effects model by means of the DerSimonian and Laird test. Primary endpoint was the time-dependent correlation between statin use and HCC incidence expressed as hazard ratio (HR), both crude and adjusted. The crude and adjusted ...[more]