Clinical Value of lncRNA MEG3 in High-Grade Serous Ovarian Cancer.
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ABSTRACT:
SUBMITTER: Buttarelli M
PROVIDER: S-EPMC7226118 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Publications
Clinical Value of lncRNA MEG3 in High-Grade Serous Ovarian Cancer.
Buttarelli Marianna M De Donato Marta M Raspaglio Giuseppina G Babini Gabriele G Ciucci Alessandra A Martinelli Enrica E Baccaro Pina P Pasciuto Tina T Fagotti Anna A Scambia Giovanni G Gallo Daniela D
Cancers 20200414 4
Long non-coding RNAs (lncRNAs) are emerging as regulators in cancer development and progression, and aberrant lncRNA profiles have been reported in several cancers. Here, we evaluated the potential of using the maternally expressed gene 3 (MEG3) tissue level as a prognostic marker in high-grade serous ovarian cancer (HGSOC), the most common and deadliest gynecologic malignancy. To the aim of the study, we measured MEG3 transcript levels in 90 pre-treatment peritoneal biopsies. We also investigat ...[more]
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