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High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases.

ABSTRACT: There is limited understanding of the specific role of high-density lipoprotein cholesterol (HDL-C) in the development of various age-related ocular diseases, despite it being a common measurable biomarker in lipid profiles. This literature review summarizes current knowledge of the role of HDL-C, if any, in pathogenesis and progression of four age-related ocular diseases, namely age-related macular degeneration (AMD), age-related cataract, glaucoma, and diabetic retinopathy (DR), and will primarily discuss epidemiological and genetic evidence.

SUBMITTER: Betzler BK 

PROVIDER: S-EPMC7226134 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases.

Betzler Bjorn Kaijun BK   Rim Tyler Hyungtaek TH   Sabanayagam Charumathi C   Cheung Chui Ming Gemmy CMG   Cheng Ching-Yu CY  

Biomolecules 20200422 4

There is limited understanding of the specific role of high-density lipoprotein cholesterol (HDL-C) in the development of various age-related ocular diseases, despite it being a common measurable biomarker in lipid profiles. This literature review summarizes current knowledge of the role of HDL-C, if any, in pathogenesis and progression of four age-related ocular diseases, namely age-related macular degeneration (AMD), age-related cataract, glaucoma, and diabetic retinopathy (DR), and will prima  ...[more]

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