Ontology highlight
ABSTRACT:
SUBMITTER: Pamedytyte D
PROVIDER: S-EPMC7226510 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Pamedytyte Daina D Simanaviciene Vaida V Dauksiene Dalia D Leipute Enrika E Zvirbliene Aurelija A Sarauskas Valdas V Dauksa Albertas A Verkauskiene Rasa R Zilaitiene Birute B
Biomolecules 20200417 4
Many miRNAs and cancer-related mutations have been proposed as promising molecular markers of papillary thyroid carcinoma (PTC). However, there are limited data on the correlation between miRNA expression, BRAF<sup>V600E</sup> mutation, and PTC recurrence. Therefore, to evaluate the potential of BRAF<sup>V600E</sup> mutation and five selected miRNAs (-146b, -222, -21, -221, -181b) in predicting PTC recurrence, these molecular markers were analyzed in 400 formalin-fixed, paraffin-embedded PTC tis ...[more]