Ontology highlight
ABSTRACT:
SUBMITTER: Lombardo SD
PROVIDER: S-EPMC7226514 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Lombardo Salvo Danilo SD Battaglia Giuseppe G Petralia Maria Cristina MC Mangano Katia K Basile Maria Sofia MS Bruno Valeria V Fagone Paolo P Bella Rita R Nicoletti Ferdinando F Cavalli Eugenio E
Brain sciences 20200329 4
The role of infections in the pathogenesis of autism spectrum disorder (ASD) is still controversial. In this study, we aimed to evaluate markers of infections and immune activation in ASD by performing a meta-analysis of publicly available whole-genome transcriptomic datasets of brain samples from autistic patients and otherwise normal people. Among the differentially expressed genes, no significant enrichment was observed for infectious diseases previously associated with ASD, including herpes ...[more]