Immune-Related Prognostic Model in Colon Cancer: A Gene Expression-Based Study.
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ABSTRACT:
SUBMITTER: Yang H
PROVIDER: S-EPMC7227137 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Immune-Related Prognostic Model in Colon Cancer: A Gene Expression-Based Study.
Yang Haojie H Jin Wei W Liu Hua H Gan Dan D Cui Can C Han Changpeng C Wang Zhenyi Z
Frontiers in genetics 20200508
Mounting evidence supports that the malignant phenotypes of cancers are defined not only by the intrinsic activity of tumor cells but also by immune cells that are recruited and activated in tumor-related microenvironment. Here, we developed a diagnostic and prognostic model for colon cancer, based on expression profiles of immune-related genes and immune cell component. As a result, we found that B cell infiltration ratio, CD4<sup>+</sup> T cells, as well as immune-related genes of <i>TRIB3</i> ...[more]
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