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Acute kidney injury after nephrectomy: a new nomogram to predict postoperative renal function.


ABSTRACT: BACKGROUND:We aimed to develop a nomogram based on preprocedural features for early prediction of acute kidney injury (AKI) and to assess the prognosis in patients after radical and partial nephrectomy. METHODS:The study included a development cohort of 1111 patients who were treated between June 2012 and June 2017 and an additional validation cohort of 356 patients who were treated between July 2017 and June 2018. Stepwise regression and logistic regression analyses were used to evaluate the association between predictors and AKI. Incorporating all independent predictors, a nomogram for postoperative AKI was developed and externally validated. Patients were followed up for 5 years to assess renal function, acute kidney disease (AKD), chronic kidney disease (CKD), hospital readmission and mortality were key prognosis we focused on. RESULTS:After multivariate logistic regression, radical nephrectomy (odds ratio (OR)?=?3.57, p?

SUBMITTER: Xu L 

PROVIDER: S-EPMC7227356 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Acute kidney injury after nephrectomy: a new nomogram to predict postoperative renal function.

Xu Lingyu L   Li Chenyu C   Zhao Long L   Zhou Bin B   Luo Congjuan C   Man Xiaofei X   Luan Hong H   Che Lin L   Wang Yanfei Y   Xu Yan Y  

BMC nephrology 20200514 1


<h4>Background</h4>We aimed to develop a nomogram based on preprocedural features for early prediction of acute kidney injury (AKI) and to assess the prognosis in patients after radical and partial nephrectomy.<h4>Methods</h4>The study included a development cohort of 1111 patients who were treated between June 2012 and June 2017 and an additional validation cohort of 356 patients who were treated between July 2017 and June 2018. Stepwise regression and logistic regression analyses were used to  ...[more]

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