Ontology highlight
ABSTRACT:
SUBMITTER: Das S
PROVIDER: S-EPMC7227421 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Das Satya S Al-Toubah Taymeyah T El-Haddad Ghassan G Strosberg Jonathan J
Expert review of gastroenterology & hepatology 20191030 11
<b>Introduction</b>: <sup>177</sup>Lutetium-[DOTA°,Tyr<sup>3</sup>]octreotate (<sup>177</sup>Lu-DOTATATE) is a type of peptide receptor radionuclide therapy that garnered FDA approval in January 2018 for the treatment of somatostatin receptor-positive gastroenteropancreatic (GEP) neuroendocrine tumor (NET) patients. The therapy approval was based on findings from the randomized international phase III NETTER-1 trial as well as outcome data from a large European registry. The mechanism of the dru ...[more]