Dataset Information

Clinical characteristics of IgG4-RD patients infected with COVID-19 in Hubei, China.

ABSTRACT:

Objective

IgG4-related disease (IgG4-RD) is an immune-mediated multi-organ, chronic and progressive disease. Therefore, we conducted a study to investigate the susceptibility of COVID-19 in IgG4-RD patients in Hubei province, and to characterize the clinical manifestation of COVID-19 in IgG4-RD patients.

Methods

A follow-up system that includes over 200 IgG4-RD patients across the country during the past ten years. A total of ninety-one patients with IgG4-RD who live in Hubei, China were identified and responded to our survey. Medical history, clinical symptoms, laboratory tests, CT imaging, and treatment were obtained through a standardized data collection form, and then independently reviewed by two investigators.

Results

2 of 91 cases were infected with COVID-19. Both of them were classified as moderate type. The symptoms such as fever and cough and radiologic features were similar to other COVID-19 patients. Neither of them episode recurrent of IgG4-RD nor progressed to severe or critical condition of COVID-19 under the condition of continuous oral low-dose of glucocorticoids. Besides, patient 2 took a long time for SARS-CoV-2 nucleic acid to turn negative.

Conclusion

IgG4-RD patients may belongs to the susceptible population of COVID-19 infection, and thus need more careful personal protection. Early identification and properly treatment are very important to prevent IgG4-RD patients with COVID-19 from progression to severe condition.

SUBMITTER: Chen Y

PROVIDER: S-EPMC7228889 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Publications

Clinical characteristics of IgG4-RD patients infected with COVID-19 in Hubei, China.

Chen Yu Y Dong Yuanji Y Cai Shaozhe S Ye Cong C Dong Lingli L

Seminars in arthritis and rheumatism 20200516 4

<h4>Objective</h4>IgG4-related disease (IgG4-RD) is an immune-mediated multi-organ, chronic and progressive disease. Therefore, we conducted a study to investigate the susceptibility of COVID-19 in IgG4-RD patients in Hubei province, and to characterize the clinical manifestation of COVID-19 in IgG4-RD patients.<h4>Methods</h4>A follow-up system that includes over 200 IgG4-RD patients across the country during the past ten years. A total of ninety-one patients with IgG4-RD who live in Hubei, Chi ...[more]

PMID: 32425259

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Dataset Information

Clinical characteristics of IgG4-RD patients infected with COVID-19 in Hubei, China.

Objective

Methods

Results

Conclusion

Publications

Clinical characteristics of IgG4-RD patients infected with COVID-19 in Hubei, China.

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