Ontology highlight
ABSTRACT:
SUBMITTER: Thillainadesan G
PROVIDER: S-EPMC7229227 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Nature communications 20200515 1
Long non-coding RNAs (lncRNAs) are components of epigenetic control mechanisms that ensure appropriate and timely gene expression. The functions of lncRNAs are often mediated through associated gene regulatory activities, but how lncRNAs are distinguished from other RNAs and recruit effector complexes is unclear. Here, we utilize the fission yeast Schizosaccharomyces pombe to investigate how lncRNAs engage silencing activities to regulate gene expression in cis. We find that invasion of lncRNA t ...[more]