Ontology highlight
ABSTRACT:
SUBMITTER: Sanchez-Canizares C
PROVIDER: S-EPMC7229655 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Sánchez-Cañizares Carmen C Prell Jürgen J Pini Francesco F Rutten Paul P Kraxner Kim K Wynands Benedikt B Karunakaran Ramakrishnan R Poole Philip S PS
Proceedings of the National Academy of Sciences of the United States of America 20200427 19
The nitrogen-related phosphotransferase system (PTS<sup>Ntr</sup>) of <i>Rhizobium leguminosarum</i> bv. <i>viciae</i> 3841 transfers phosphate from PEP via PtsP and NPr to two output regulators, ManX and PtsN. ManX controls central carbon metabolism via the tricarboxylic acid (TCA) cycle, while PtsN controls nitrogen uptake, exopolysaccharide production, and potassium homeostasis, each of which is critical for cellular adaptation and survival. Cellular nitrogen status modulates phosphorylation ...[more]