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Metabolomics Reveals Discrimination of Chinese Propolis from Different Climatic Regions.

ABSTRACT: The chemical profiles of propolis vary greatly due to the botanic sources and geographic origins, which limit its standardization for modern usages. Here, we proposed a reliable 1H NMR-based metabolomic approach, to discriminate the function and quality of Chinese propolis. A total 63 Chinese propolis samples from different temperate regions were collected and extracted for NMR analysis. Twenty-one compositions in ethanol extracts were assigned based on characteristic chemical shifts and previous literature reports. Significant geographic indicators were identified after the PCA and orthogonal partial least squares discriminant analysis (OPLS-DA) analysis of the obtained 1H NMR data. It was found that the composition discriminations arose from long-term acclimation of the different climates of botanic origin and caused the differences in the biological activities. This study provides us a reasonable instruction for the quality control of Chinese propolis.

SUBMITTER: Wang T

PROVIDER: S-EPMC7230208 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Metabolomics Reveals Discrimination of Chinese Propolis from Different Climatic Regions.

Wang Tongtong T Liu Quanhui Q Wang Min M Zhang Limin L

Foods (Basel, Switzerland) 20200414 4

The chemical profiles of propolis vary greatly due to the botanic sources and geographic origins, which limit its standardization for modern usages. Here, we proposed a reliable <sup>1</sup>H NMR-based metabolomic approach, to discriminate the function and quality of Chinese propolis. A total 63 Chinese propolis samples from different temperate regions were collected and extracted for NMR analysis. Twenty-one compositions in ethanol extracts were assigned based on characteristic chemical shifts ...[more]

PMID: 32295098

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