Ontology highlight
ABSTRACT:
SUBMITTER: Glas GJ
PROVIDER: S-EPMC7230289 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Glas Gerie J GJ Horn Janneke J Binnekade Jan M JM Hollmann Markus W MW Muller Jan J Cleffken Berry B Colpaert Kirsten K Dixon Barry B Juffermans Nicole P NP Knape Paul P Levi Marcel M MM Loef Bert G BG Mackie David P DP Malbrain Manu L N G MLNG Preckel Benedikt B Reidinga Auke C AC van der Sluijs K F KF Schultz Marcus J MJ
Journal of clinical medicine 20200325 4
<h4>Background</h4>Pulmonary hypercoagulopathy is intrinsic to inhalation trauma. Nebulized heparin could theoretically be beneficial in patients with inhalation injury, but current data are conflicting. We aimed to investigate the safety, feasibility, and effectiveness of nebulized heparin.<h4>Methods</h4>International multicenter, double-blind, placebo-controlled randomized clinical trial in specialized burn care centers. Adult patients with inhalation trauma received nebulizations of unfracti ...[more]