Ontology highlight
ABSTRACT:
SUBMITTER: Njiomegnie GF
PROVIDER: S-EPMC7230811 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Njiomegnie Gaitan Fabrice GF Read Scott A SA Fewings Nicole N George Jacob J McKay Fiona F Ahlenstiel Golo G
Journal of clinical medicine 20200406 4
Hepatitis C virus (HCV) infection develops into chronic hepatitis in over two-thirds of acute infections. While current treatments with direct-acting antivirals (DAAs) achieve HCV eradication in >95% of cases, no vaccine is available and re-infection can readily occur. Natural killer (NK) cells represent a key cellular component of the innate immune system, participating in early defence against infectious diseases, viruses, and cancers. When acute infection becomes chronic, however, NK cell fun ...[more]