Genetics and Epigenetics of Atopic Dermatitis: An Updated Systematic Review.

ABSTRACT:

Background

Atopic dermatitis is a common inflammatory skin disorder that affects up to 15-20% of the population and is characterized by recurrent eczematous lesions with intense itching. As a heterogeneous disease, multiple factors have been suggested to explain the nature of atopic dermatitis (AD), and its high prevalence makes it necessary to periodically compile and update the new information available. In this systematic review, the focus is set at the genetic and epigenetic studies carried out in the last years.

Methods

A systematic literature review was conducted in three scientific publication databases (PubMed, Cochrane Library, and Scopus). The search was restricted to publications indexed from July 2016 to December 2019, and keywords related to atopic dermatitis ge

SUBMITTER: Martin MJ 

PROVIDER: S-EPMC7231115 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature