Dataset Information

Biohumoral Indicators Influenced by Physical Activity in the Elderly.

ABSTRACT: In the scientific landscape, there is a growing interest in defining the role of several biomolecules and humoral indicators of the aging process and in the modifications of these biomarkers induced by physical activity and exercise. The main aim of the present narrative review is to collect the available evidence on the biohumoral indicators that could be modified by physical activity (PA) in the elderly. Online databases including Pubmed, Web of science (Medline), and Scopus were searched for relevant articles published in the last five years in English. Keywords and combination of these used for the search were the following: "biological", "indicators", "markers", "physical", "activity", and "elderly". Thirty-four papers were analyzed for inclusion. Twenty-nine studies were included and divided into four categories: cardiovascular (CV) biomarkers, metabolic biomarkers, inflammatory markers-oxidative stress molecules, and other markers. There are many distinct biomarkers influenced by PA in the elderly, with promising results concerning the metabolic and CV indexes, as a growing number of studies demonstrate the role of PA on improving parameters related to heart function and CV risk like atherogenic lipid profile. Furthermore, it is also a verified hypothesis that PA is able to modify the inflammatory status of the subject by decreasing the levels of pro-inflammatory cytokines, including interleukin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-?). PA seems also to be able to have a direct effect on the immune system. There is a strong evidence of a positive effect of PA on the health of elderly people that could be evidenced and "quantified" by the modifications of the levels of several biohumoral indicators.

SUBMITTER: Fossati C

PROVIDER: S-EPMC7231282 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Biohumoral Indicators Influenced by Physical Activity in the Elderly.

Fossati Chiara C Torre Guglielmo G Borrione Paolo P Giombini Arrigo A Fagnani Federica F Turchetta Matteo M Albo Erika E Casasco Maurizio M Parisi Attilio A Pigozzi Fabio F

Journal of clinical medicine 20200413 4

In the scientific landscape, there is a growing interest in defining the role of several biomolecules and humoral indicators of the aging process and in the modifications of these biomarkers induced by physical activity and exercise. The main aim of the present narrative review is to collect the available evidence on the biohumoral indicators that could be modified by physical activity (PA) in the elderly. Online databases including Pubmed, Web of science (Medline), and Scopus were searched for ...[more]

PMID: 32295038

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Project description:BackgroundDisability in Activities of Daily Living (ADL) is an adverse outcome of frailty that places a burden on frail elderly people, care providers and the care system. Knowing which physical frailty indicators predict ADL disability is useful in identifying elderly people who might benefit from an intervention that prevents disability or increases functioning in daily life. The objective of this study was to systematically review the literature on the predictive value of physical frailty indicators on ADL disability in community-dwelling elderly people.MethodsA systematic search was performed in 3 databases (PubMed, CINAHL, EMBASE) from January 1975 until April 2010. Prospective, longitudinal studies that assessed the predictive value of individual physical frailty indicators on ADL disability in community-dwelling elderly people aged 65 years and older were eligible for inclusion. Articles were reviewed by two independent reviewers who also assessed the quality of the included studies.ResultsAfter initial screening of 3081 titles, 360 abstracts were scrutinized, leaving 64 full text articles for final review. Eventually, 28 studies were included in the review. The methodological quality of these studies was rated by both reviewers on a scale from 0 to 27. All included studies were of high quality with a mean quality score of 22.5 (SD 1.6). Findings indicated that individual physical frailty indicators, such as weight loss, gait speed, grip strength, physical activity, balance, and lower extremity function are predictors of future ADL disability in community-dwelling elderly people.ConclusionsThis review shows that physical frailty indicators can predict ADL disability in community-dwelling elderly people. Slow gait speed and low physical activity/exercise seem to be the most powerful predictors followed by weight loss, lower extremity function, balance, muscle strength, and other indicators. These findings should be interpreted with caution because the data of the different studies could not be pooled due to large variations in operationalization of the indicators and ADL disability across the included studies. Nevertheless, our study suggests that monitoring physical frailty indicators in community-dwelling elderly people might be useful to identify elderly people who could benefit from disability prevention programs.

Project description:Adult playfulness is a personality trait that enables people to frame or reframe everyday situations in such a way that they experience them as entertaining, intellectually stimulating, or personally interesting. Earlier research supports the notion that playfulness is associated with the pursuit of an active way of life. While playful children are typically described as being active, only limited knowledge exists on whether playfulness in adults is also associated with physical activity. Additionally, existing literature has not considered different facets of playfulness, but only global playfulness. Therefore, we employed a multifaceted model that allows distinguishing among Other-directed, Lighthearted, Intellectual, and Whimsical playfulness. For narrowing this gap in the literature, we conducted two studies addressing the associations of playfulness with health, activity, and fitness. The main aim of Study 1 was a comparison of self-ratings (N = 529) and ratings from knowledgeable others (N = 141). We tested the association of self- and peer-reported playfulness with self- and peer-reported physical activity, fitness, and health behaviors. There was a good convergence of playfulness among self- and peer-ratings (between r = 0.46 and 0.55, all p < 0.001). Data show that both self- and peer-ratings are differentially associated with physical activity, fitness, and health behaviors. For example, self-rated playfulness shared 3% of the variance with self-rated physical fitness and 14% with the pursuit of an active way of life. Study 2 provides data on the association between self-rated playfulness and objective measures of physical fitness (i.e., hand and forearm strength, lower body muscular strength and endurance, cardio-respiratory fitness, back and leg flexibility, and hand and finger dexterity) using a sample of N = 67 adults. Self-rated playfulness was associated with lower baseline and activity (climbing stairs) heart rate and faster recovery heart rate (correlation coefficients were between -0.19 and -0.24 for global playfulness). Overall, Study 2 supported the findings of Study 1 by showing positive associations of playfulness with objective indicators of physical fitness (primarily cardio-respiratory fitness). The findings represent a starting point for future studies on the relationships between playfulness, and health, activity, and physical fitness.

Dataset Information

Biohumoral Indicators Influenced by Physical Activity in the Elderly.

Publications

Biohumoral Indicators Influenced by Physical Activity in the Elderly.

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