Comparative clinical trials in psychotherapy: Have large effects been replicated?

ABSTRACT: AIMS:The purpose of this review is to examine the replication attempts of psychotherapy clinical trials for depression and anxiety. We focus specifically on replications of trials that exhibit large differences between psychotherapies. The replicability of these trials is especially important for meta-analysis, where the inclusion of false-positive trials can lead to erroneous conclusions about treatment efficacy. METHODS:Standard replication criteria were developed to distinguish direct from conceptual replication methodologies. Next, an exhaustive literature search was conducted for published meta-analyses of psychotherapy comparisons. Trials that exhibited large effects (d > 0.8) were culled from these meta-analyses. For each trial, a cited replication was conducted to determine if the

SUBMITTER: Frost ND 

PROVIDER: S-EPMC7232123 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature