Ontology highlight
ABSTRACT:
SUBMITTER: Park M
PROVIDER: S-EPMC7232685 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Park Mira M Lee Jung Wun JW Park Taesung T Lee SeungYeoun S
BioMed research international 20200509
In this study, we propose a simple and computationally efficient method based on the multifactor dimensional reduction algorithm to identify gene-gene interactions associated with the survival phenotype. The proposed method, referred to as KM-MDR, uses the Kaplan-Meier median survival time as a classifier. The KM-MDR method classifies multilocus genotypes into a binary attribute for high- or low-risk groups using median survival time and replaces balanced accuracy with log-rank test statistics a ...[more]