Ontology highlight
ABSTRACT:
SUBMITTER: Hsu YO
PROVIDER: S-EPMC7232862 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Hsu Yun-Shiuan O YO Wu I-Wen IW Chang Shang-Hung SH Lee Cheng-Chia CC Tsai Chung-Ying CY Lin Chan-Yu CY Lin Wan-Ting WT Huang Yu-Tung YT Wu Chao-Yi CY Kuo George G Hsiao Chih-Yen CY Lin Hsing-Lin HL Yang Chih-Chao CC Yen Tzung-Hai TH Chen Yung-Chang YC Hung Cheng-Chieh CC Tian Ya-Chong YC Kuo Chang-Fu CF Yang Chih-Wei CW Anderson Gerard F GF Yang Huang-Yu HY
Clinical pharmacology and therapeutics 20191217 5
Hyperuricemia has been associated with chronic kidney disease (CKD) progression. The antihyperuricemic febuxostat's potential renoprotective effect has been demonstrated in stage 1-3 CKD. Large-scale studies comparing the renoprotective potential of febuxostat and allopurinol in advanced CKD are lacking. We exclusively selected 6,057 eligible patients with predialysis stage 5 CKD prescribed either febuxostat or allopurinol using the National Health Insurance Research Database in Taiwan during 20 ...[more]